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. 2021 Sep 29;11:19302. doi: 10.1038/s41598-021-97092-y

Table 2.

Study medication exposure during pregnancy and the risk of prematurity by sub-categories of prematurity.

Characteristics Prematurity < 37 completed weeks of gestation n = 15,688
Extreme prematurity < 28 weeks of gestation Moderate prematurity 28–31 weeks of gestation Near-term prematurity 32–36 weeks of gestation
n (%)
Yes n = 653 No n = 233,247 Yes n = 1291 No n = 232,609 Yes No
Study medication exposure
DHEa 1 (0.15) 77 (0.00) 0 (0.00) 78 (0.01) 18 (0.01) 60 (0.00)
Triptansb 2 (0.31) 524 (0.22) 3 (0.23) 523 (0.22) 56 (0.41) 470 (0.21)

aDihydroergotamine; bIncluding almotriptan, eletriptan, naratriptan, rizatriptan, sumatriptan, and zolmitriptan.