Table 7.

Association between DHE exposure before or during pregnancy and the risk of prematurity by categories of DHE exposure.

Characteristics	Prematurity < 37 completed weeks of gestation
	Yes n = 15,688	No n = 218,212	Crude RR (95% CI)	Adjusted RR (95% CI)
	n (%)
Study medication exposure during the pregnancy
DHEa prior to pregnancy only	8 (0.05)	83 (0.04)	1.19 (0.78–1.82)	1.12 (0.73–1.72)
DHE prior and during pregnancy	13 (0.08)	65 (0.03)	2.65 (1.11–6.33)	2.59 (1.17–5.73)
DHE during pregnancy only	6 (0.04)	72 (0.03)	1.30 (0.79–2.14)	1.26 (0.69–2.30)

Adjusted for all variables included in Table 1.

^aDihydroergotamine.