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. 2021 Sep 29;11:19302. doi: 10.1038/s41598-021-97092-y

Table 8.

Association between DHE exposure before or during pregnancy and the risk of LBW by categories of DHE exposure.

Characteristics LBW < 2500 g at birth
Yes n = 11,875 No n = 222,025 Crude RR (95% CI) Adjusted RR (95% CI)
n (%)
Study medication exposure during pregnancy
DHEa prior to pregnancy only 7 (0.06) 84 (0.04) 1.45 (0.71–2.96) 1.41 (0.73–2.72)
DHE prior and during pregnancy 8 (0.07) 70 (0.03) 2.30 (0.76–6.96) 2.21 (0.81–6.03)
DHE during pregnancy only 5 (0.04) 73 (0.03) 1.33 (0.66–2.68) 1.25 (0.68–2.30)

Adjusted for all variables included in Table 3.

aDihydroergotamine.