Table 3.
Statistical concurrence observed across ReHo studies on OCD.
| Region | Local maximum | Cluster | Jackknife sensitivity analysis (combination of studies detecting the differences) | |||||
|---|---|---|---|---|---|---|---|---|
| MNI Coordinates | SDM-Z | P | Number of voxels | Breakdown (number of voxel) | ||||
| Higher ReHo (OCD > HCS) | ||||||||
| Left inferior frontal gyrus | −48 | 34 | 0 | 3.203 | ~0 | 2023 | Left inferior frontal gyrus (1663) | 10 out of 10 |
| Left middle frontal gyrus (202) | ||||||||
| Left insula (158) | ||||||||
| Right inferior frontal gyrus | 48 | 36 | −10 | 1.942 | 0.000668841 | 408 | Right inferior frontal gyrus (370) | 8 out of 10 |
| Right middle frontal gyrus (38) | ||||||||
| Left orbitofrontal gyrus | −10 | 50 | −16 | 1.792 | 0.001478572 | 587 | Left orbitfrontal gyrus (339) | 8 out of 10 |
| Right orbitfrontal gyrus (248) | ||||||||
| Lower ReHo (OCD < HCS) | ||||||||
| Right supplementary motor area | 6 | −20 | 66 | −1.996 | 0.000082057 | 1443 | Left paracentral lobule (327) | 10 out of 10 |
| Left supplementary motor area (129) | ||||||||
| Right paracentral lobule (363) | ||||||||
| Right precentral gyrus (96) | ||||||||
| Right supplementary motor area (528) | ||||||||
| Left cerebellum | −14 | −52 | −24 | −1.605 | 0.001129702 | 269 | Left cerebellum (269) | 9 out of 10 |
| Right cerebellum | 20 | −58 | −26 | −1.604 | 0.001129702 | 160 | Left cerebellum (160) | 9 out of 10 |
HCS, healthy control subjects; MNI, Montreal Neurological Institute; OCD, obsessive-compulsive disorder; ReHo, regional homogeneity; SDM, seed-based d mapping.