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. 2021 Sep 16;9:741074. doi: 10.3389/fcell.2021.741074

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Copyright © 2021 Pan, Du, Li, Shen, Liu, Li and Hu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Kinetics process of DNA damage repair in miR-29b-3p knockdown or overexpressed A549 cells. (A) Graph shows quantification of 53BP1 and yH2AX foci in miR-29b-3p knockdown and negative control A549 cells exposed to 1 Gy X-ray. (B) The numbers of 53BP1 and yH2AX foci in 50 cells of each group were counted for each time point. (C) Graph shows quantification of 53BP1 and yH2AX foci in miR-29b-3p overexpressed and negative control A549 cells exposed to 1 Gy X-ray. (D) The numbers of 53BP1 and yH2AX foci in 50 cells of each group were counted for each time point. Ctrl, unirradiated groups; NC, negative control. Significance was determined by unpaired t-test. *P < 0.05; **P < 0.01.