TABLE 2.
Summary comparison of phenotypic and genotypic test results from 81 Salmonella enterica isolates from Cambodian informal markets, 2018–2019a.
|
No. of test results
|
||||||||
|
Phenotype: resistant
|
Phenotype: susceptible
|
|||||||
| Antibiotic | Genotype: resistant | Genotype: susceptible | Genotype: resistant | Genotype: susceptible | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) |
| Aminoglycosides | ||||||||
| Gentamicin (GEN) | 2 | 0 | 79 | 100 | 100 | 100 | 100 | |
| Streptomycin (STR) | 15 | 1 | 15 | 50 | 93.8 | 76.9 | 50.0 | 98.0 |
| Beta-lactam/beta-lactam inhibitor | ||||||||
| Amoxicillin-clavulanic acid (AMC) | 0 | 0 | 0 | 81 | DBZb | 100 | DBZ | DBZ |
| Cephems | ||||||||
| Cefoxitin (FOX) | 0 | 2 | 0 | 79 | 0 | 100 | DBZ | 97.5 |
| Ceftriaxone (CRO) | 2 | 1 | 0 | 78 | 66.7 | 100 | 100 | 98.7 |
| Ceftiofur (XNL) | 2 | 1 | 0 | 78 | 66.7 | 100 | 100 | 98.7 |
| Penicillin | ||||||||
| Ampicillin (AMP) | 30 | 0 | 0 | 51 | 100 | 100 | 100 | 100 |
| Sulfonamide | ||||||||
| Sulfisoxazole (FIS) | 0 | 0 | 0 | 81 | DBZ | 100 | DBZ | DBZ |
| Trimethoprim | ||||||||
| Trimethoprim-sulfamethoxazole (SXT) | 13 | 0 | 0 | 68 | 100 | 100 | 100 | 100 |
| Macrolide | ||||||||
| Azithromycin (AZM) | 0 | 0 | 0 | 81 | DBZ | 100 | DBZ | DBZ |
| Phenicol | ||||||||
| Chloramphenicol (CHL) | 13 | 1 | 0 | 67 | 92.9 | 100 | 100 | 98.5 |
| Quinolones | ||||||||
| Ciprofloxacin (CIP) | 0 | 0 | 22 | 59 | DBZ | 72.8 | DBZ | DBZ |
| Nalidixic acid (NAL) | 0 | 0 | 0 | 81 | DBZ | 100 | DBZ | DBZ |
| Tetracycline | ||||||||
| Tetracycline (TET) | 38 | 0 | 0 | 43 | 100 | 100 | 100 | 100 |
| Total | 115 | 6 | 37 | 976 | 95.1 | 96.4 | 75.7 | 99.4 |
aPPV, positive predictive value; NPV, negative predictive value.
bDivision by zero (DBZ): values were not able to be calculated when phenotypic resistance was not observed due to division by zero.