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. 2021 Sep 16;9:680713. doi: 10.3389/fcell.2021.680713

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Copyright © 2021 Xie, Zhang, Mao, Zhang and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Models of four known lncRNA molecular mechanisms of action in myocardial infarction. (A) Decoy. lncRNAs can act as sponges to interact with regulatory proteins or RNAs away from their targets. (B) Guide. lncRNAs can recruit and combine regulatory proteins or DNAs through molecular interactions and guiding the complexes to the specific targets. (C) Signal. lncRNAs respond to specific stimuli and participant in the regulation of gene expression by regulating signaling pathways through cis- or trans- way. (D) Scaffold. lncRNAs may serve as scaffolds to bring proteins together in biological regulation.