TABLE 1.

LncRNAs with characterized functions and target genes in myocardial infarction.

LncRNA	Target	Function	References
CARL	miR-539/PHB2	Inhibit mitochondrial fission and myocardial apoptosis in MI.	Wang et al., 2014
APF	miR-188-3p/ATG7	Regulates autophagic program and autophagic cell death after MI.	Wang K. et al., 2015
NRF	miR-873/RIPK1-RIPK3	Regulate cardiomyocyte necrosis and myocardial injury in I/R.	Wang et al., 2016
H19	miR-103/107/FADD	Regulate programmed Necrosis and Myocardial I/R Injury	Wang J.X. et al., 2015
	miR-877-3p/Bcl-2	Inhibit the mitochondrial apoptotic pathway in myocardial	Li et al., 2019
	miR-675/PPARα	Regulate cell death and IR injury	Luo et al., 2019
CAIF	p53-mediated myocardin	Repress autophagic cell death and alleviate MI.	Liu et al., 2018
Kcnq1ot1	RUNX3	Recruits DNMT1 to the RUNX3 promoter region and regulates CMEC viability and inflammatory response during MI.	Wang et al., 2019
CPR	MCM3	Interact and recruit DNMT3A to the CpG island of MCM3 promoter, then inhibit cardiomyocyte proliferation and cardiac function after MI	Ponnusamy et al., 2019
Sarrah	NRF2	Recruit CRIP2 and p300 to form complex and regulate cardiomyocytes apoptosis in AMI.	Trembinski et al., 2020
FAF	FGF9/FGFR2/PI3K/Akt	Regulate myocardial cell apoptosis in AMI.	Shi et al., 2019
SLC8A1-AS1	SLC8A1/cGMP-PKG	Reduce infarct size and ischemia damage in AMI.	Guo et al., 2019
Airn	Igf2bp2	Affects the translation of Igf2bp2, silencing Airn can increase apoptosis and affect the physiological function of cardiomyocytes.	Hosen et al., 2018
ZFAS1	SERCA2a	Inhibitor of SERCA2a and limits systolic function during MI.	Zhang et al., 2018
Ahit	SUZ12	Downregulating the expression of MEF2A and preventing cardiac hypertrophy through epigenomic modulation.	Yu J. et al., 2020
ANRIL	WDR5-HDAC3	Form protein complexes and increase ROS level.	Zhang et al., 2020