Table 2.
Analyzation of clinical treatments and results (patients more than six)
| Author (Year) |
Type of alopecia | Patient N (M, F) Age [Mean] |
Intervention (Sort/ Site) | Outcome measurement | Result | Adverse events |
|---|---|---|---|---|---|---|
| Kim (2004) (2) [31] |
AGA | 6 (2, 4) [49.6] |
1. HM: Honey pill (Biotae Cacumen, Mori Folium, Phyllostachydis Folium, Ginkgo Folium, Pini Polium, Glycyrrhizae Radix, Ginseng Radix, Pulsatillae Radix, Kochiae Fructus, Moutan Cortex, Lycii Fructus, Rehmanniae Radix Preparat, Poria (Hoelen), Corni Fructus, Sesami Semen Nigrum, Prunellae Spica, Acanthopanacis Cortex, Alismatis Rhizoma, Taraxci Herba, Laminariae Thallus, Biotae Semen) 2. External medicine or products: Herbal spray (Biotae Cacumen, Mori Folium, Phyllostachydis Folium, Ginkgo Folium, Pini Polium, Glycyrrhizae Radix, Ginseng Radix, Pulsatillae Radix, Kochiae Fructus, Houttuyniae Herba, Lycii Fructus, Glycinis Semen Nigra, Sesami Semen Nigrum, Prunellae Spica, Acanthopanacis Cortex, Cannabis Folium, Laminariae Thallus extract) |
1. Magnifying glass 2. Questionnaire (Effect on the herb medicine prescription) 3. Hair loss during shampooing 4. Hair regrowth change |
1. Improved 2. Improved 3. Improved 4. Improved |
None |
| Yi (2006) [32] |
AGA | 82 (82, 0) [30 ± 5.5] |
1. Atx: Oh-Shu acupoint (According to the symptoms) 2. Phx: HP, CF etc./ ST8, GV23, GV21, GV20, BL6, EX-HN1 3. External medicine or products: Shampoo (Blue spring from Dr.hoo Corp) |
1. Visual evaluation&Pictures 2. Questionnaire (Patient self-assessment) 3. Investigator assessment |
1. Improved 2. Improved 3. Improved |
N.R |
| Lee (2013) [33] |
AA | 1,050‡ (714, 336) [30.67 ± 9.03] |
1. HM: Unknown 2. Atx: GV20, EX-HN1, GB5, ST8, PC6, HT8, ST36, BL66 etc. (According to the symptoms) 3. External medicine or product: Oriental hair care products (Balmers M shampoo, M tonic, 701 serum) |
1. Visual evaluation&Pictures 2. Magnifying glass 3. Questionnaire (Parietal Fever, Sebum, Keratin, Pruritus, Hair elasticity, Change of hair loss volume) |
1. Improved (56.2%) (p = 0.003) 2. 13.14 ± 4.13→ 13.82 ± 4.12 (p < 0.001) 3. Improved§ |
N.R |
| Hong (2013) [34] |
FA | 30 (30, 0) [31.73 ± 6.34] |
1. HM: Gagam Chengyoung-tang 2. Atx: GV20, GV21, GV22, GV23, ST8, HT8, ST36 |
1. Questionnaire (1) Cold-heat questionnaire (2) Hair and scalp questionnaire 2. Magnifying glass |
1. (1) 5.35 ± 2.82 → 4.21 ± 2.29 (p = 0.082) (2) 4.5 ± 1.28 → 1.6 ± 1.10 (p < 0.001) 2. 1.43 ± 0.27 → 1.61 ± 0.24 (p < 0.001) |
N.R |
| Choi (2019) (2) [20] |
AA | 222 (100, 122) [35.3] |
1. HM: Gagam Hyeongbangpaedok-san, Gagam Hwajung-hwan, Gagam Jaeumbaekbo-hwan 2. Atx: GV20, EX-HN1, GB5, PC6, TE5, ST36, KI3 |
1. SALT score∥ | 1. Improved (77.9%) | Diarrhea |
| Starace (2019) [35] |
AGA, TE (AGA = 43, TE = 7) |
50 (36, 14) [38.6] |
1. Microneedling (1) Before rolling 1 h ago: Lidocaine and Prilocaine, Tetracaine cream (2) Rolling: Affected areas in longitudinal, vertical, and diagonal directions (3) After rolling: Antiseptic solution, antibiotic cream |
1. Magnifying glass (Trichoscopy) 2. Pull test 3. Iconography |
1. Increased frontal and vertex median density 2. Improved 3. Improved |
None |
‡1,050 people conducted an initial survey, but 153 people conducted a retrospective survey in the actual paper.
§Improved patient rate (%): Parietal Fever (37.3%), Sebum (19.6%), Keratin (23.5%), Pruritus (30.7%), Hair elasticity (83%), Change of hair loss volume (31.4%).
∥SALT score was calculated according to these categories (Age and Sex Distribution, Clinical Type of AA, Extent of AA, Duration before Visit, Age of onset, Age of first visit, The period until Regrowth of Terminal Hair, The Period until Cured, Associated immunological disease, Previous treatments, Family history, Relapse) but the p-value of Age and Sex Distribution, Age of onset, Age of first visit, Associated immunological disease, Previous treatments, Family history is over 0.005.