Figure 4.

Cumulative probability of 24-week CDW in propensity score–matched Q6W and Q4W patients (all matched patients). CDW was defined as an increase of ⩾0.5 point from a baseline EDSS score of ⩾6.0, ⩾1.0 point from a baseline EDSS score of ⩾1.0 to  < 6.0, or ⩾1.5 points from a baseline EDSS score of 0.0, confirmed after 24 weeks. Cox p-value equivalent to log-rank test. Dashed lines indicate the 95% CIs.

CDW, confirmed disability worsening; CI, confidence interval; EDSS, Expanded Disability Status Scale; Q4W, every 4 weeks; Q6W, every 6 weeks.