TABLE 3.

Guidelines for evaluating the clinical benefits of PneumoSeq.

Clinical benefit of PneumoSeq	Guidance from PneumoSeq in the management of patients
Initiation of targeted treatment	PneumoSeq detected pathogens and guided targeted antimicrobial treatment.
Pathogen identification or treatment confirmation	PneumoSeq detected pathogens, either consistent with conventional tests or not, and/or PneumoSeq confirmed that the initial empirical treatment could be continued.
Treatment De-escalation	Antimicrobial drugs were de-escalated or discontinued according to the results of PneumoSeq.
No clinical benefit	Antimicrobial drugs were adjusted according to conventional tests or physician experience.