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. 2021 Sep 16;11:698883. doi: 10.3389/fcimb.2021.698883

Table 2.

Cytotoxic activity of five depsides (1-5) expressed as hemolytic percentages at the highest tested concentration (100 µg/ml) and growth inhibition of HeLa cells.

Compounds Hemolytic activity (%) Growth inhibition of HeLa cells (% inhibition)
at 100 µg/ml at 6.125 µg/ml at 12.5 µg/ml at 100 µg/ml
1 0 22.2 ± 2.8 nd 88.0 ± 2.1
2 0.4 ± 0.01 nd 14.8 ± 1.6 44.5 ± 6.5
3 4.0 ± 0.02 nd 11.0 ± 0.9 45.3 ± 3.5
4 0 nd nd 84.5 ± 6.8
5 0.5 ± 0.27 nd nd 70.0 ± 2.3

nd, not determined.

The results are expressed as mean of inhibition percentages ± standard deviations (SD) depending on the tested concentrations of the compounds (100, 12.5, or 6.25 µg/ml). All experiments were performed in duplicate with at least two replicate experiments.