Table 2.
Cytotoxic activity of five depsides (1-5) expressed as hemolytic percentages at the highest tested concentration (100 µg/ml) and growth inhibition of HeLa cells.
| Compounds | Hemolytic activity (%) | Growth inhibition of HeLa cells (% inhibition) | ||
|---|---|---|---|---|
| at 100 µg/ml | at 6.125 µg/ml | at 12.5 µg/ml | at 100 µg/ml | |
| 1 | 0 | 22.2 ± 2.8 | nd | 88.0 ± 2.1 |
| 2 | 0.4 ± 0.01 | nd | 14.8 ± 1.6 | 44.5 ± 6.5 |
| 3 | 4.0 ± 0.02 | nd | 11.0 ± 0.9 | 45.3 ± 3.5 |
| 4 | 0 | nd | nd | 84.5 ± 6.8 |
| 5 | 0.5 ± 0.27 | nd | nd | 70.0 ± 2.3 |
nd, not determined.
The results are expressed as mean of inhibition percentages ± standard deviations (SD) depending on the tested concentrations of the compounds (100, 12.5, or 6.25 µg/ml). All experiments were performed in duplicate with at least two replicate experiments.