Table 1.

Regional changes in cortical thickness in the gout group compared with HCs.

Contrast		Cortical region	Size (mm2)	xyz peak (MNI)	p -Value
Gout > HCs	Left	Postcentral	1.40	−35.5/−30.2/54.2	0.015*
		Supramarginal	13.19	−47.9/−53.2/−32.2	0.046*
	Right	Medial temporal	6.87	59.0/−28.8/−16.5	0.025*
		Medial orbitofrontal	9.85	12.6/26.6/−16.2	0.042*
Gout < HCs	Left	Insula	2.81	−35.4/−10.4/−2.0	0.017*
		Superior frontal	10.46	−17.0/41.1/36.8	0.029*
	Right	Pericalcarine	4.98	11.5/−85.0/9.1	0.020*
		Precentral	5.29	21.4/−26.4/52.3	0.031*

HCs, healthy controls; MNI, Montreal Neurological Institute.

Based on the Desikan–Killiany Atlas with 68 parcels bilaterally.