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. 2021 Sep 16;12:698046. doi: 10.3389/fgene.2021.698046

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Copyright © 2021 Duan, Jiang, Liu, Liu, Ma, Xie, Wang, Cheng, Zou, Wu, Liu, Gao, Li and Xie.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Functional annotation of host genes of differentially expressed (DE) up-regulated circular RNAs (circRNA) with the top 10 rich ration of cellular component (CC) (A) and molecular function (MF) (B). The abscissa is the rich ration [(DE genes of the term /all the DE genes)/(all the annotated gene of the term / all the annotated gene)]; the Y-axis shows the terms enriched. A higher rich ration correlates with lower p-values. Circle size represents the number of enriched genes, and the color indicates the degree of enrichment, with red representing the highest degree of enrichment.