TABLE 4.

Results of association between FADS1–3 polymorphisms and ESRD.

Gene	Locus	Model	Genotype	Controls	Patients	Odds ratio	P value
FADS1	rs174556	Allele	C	204(59.6%)	203(61.9%)	1	0.55
			T	138(40.4%)	125(38.1%)	0.91 (0.67–1.24)
		Codominant	CC	47(27.5%)	48(29.3%)	1.00	0.61
			CT	110(64.3%)	107(65.2%)	0.95 (0.59–1.54)
			TT	14(8.2%)	9(5.5%)	0.63 (0.25–1.59)
		Dominant	CC	47(27.5%)	48(29.3%)	1.00	0.71
			CT + TT	124(72.5%)	116(70.7%)	0.92 (0.57–1.47)
		Recessive	CC + CT	157(91.8%)	155(94.5%)	1.00	0.33
			TT	14(8.2%)	9(5.5%)	0.65 (0.27–1.55)
		Overdominant	CC + TT	61(35.7%)	57(34.8%)	1.00	0.86
			CT	110(64.3%)	107(65.2%)	1.04 (0.66–1.63)
		Log-additive				086 (0.59–1.27)	0.46
FADS2	rs99780	Allele	C	239(69.9%)	240(73.2%)	1	0.35
			T	103(30.1%)	88(26.8%)	0.85 (0.61–1.19)
		Codominant	CC	85(49.7%)	88(53.7%)	1.00	0.62
			CT	69(40.4%)	64(39%)	0.90 (0.59–1.54)
			TT	17(9.9%)	12(7.3%)	0.68 (0.31–1.51)
		Dominant	CC	85(49.7%)	88(53.7%)	1.00	0.47
			CT + TT	86(50.3%)	76(46.3%)	0.85 (0.56–1.31)
		Recessive	CC + CT	154(90.1%)	152(92.7%)	1.00	0.39
			TT	17(9.9%)	12(7.3%)	0.72 (0.33–1.55)
		Overdominant	CC + TT	102(59.6%)	100(61%)	1.00	0.8
			CT	69(40.4%)	64(39%)	0.95 (0.61–1.47)
		Log-additive				0.85 (0.61–1.19)	0.35
FADS3	rs7115739	Allele	G	300(87.7%)	309(94.2%)	1	0.004
			T	42(12.3%)	19(5.8%)	0.44 (0.25–0.77)
		Codominant	GG	134(78.4%)	146(89%)	1.00	0.019
			GT	32(18.7%)	17(10.4%)	0.49 (0.26–0.92)
			TT	5(2.9%)	1(0.6%)	0.18 (0.02–1.6)
		Dominant	GG	134(78.4%)	146(89%)	1.00	0.0078
			GT + TT	37(21.6%)	18(11%)	0.45 (0.24–0.82)
		Recessive	GG + GT	166(97.1%)	163(99.4%)	1.00	0.095
			TT	5(2.9%)	1(0.6%)	0.2 (0.02–1.76)
		Overdominant	GG + TT	139(81.3%)	147(89.6%)	1.00	0.029
			GT	32(18.7%)	17(10.4%)	0.5 (0.27–0.94)
		Log-additive				0.47 (0.27–0.82)	0.005