Table 2.
Genes included in the seven-gene prognostic signature.
| Gene symbol | Log2 FCa | Coefficientb | HR (95% CI)b | P b |
|---|---|---|---|---|
| B3GALT5-AS1 | 1.18 | -0.06761697 | 0.93 (0.41-2.15) | 0.87 |
| DNER | 1.60 | 0.18801037 | 1.21 (0.39-3.73) | 0.74 |
| CSN1S1 | 1.61 | 0.28358112 | 1.33 (1.03-4.30) | 0.11 |
| KIF5A | 1.10 | 0.36011127 | 1.43 (0.79-2.61) | 0.24 |
| SIX3 | 1.28 | 0.57677377 | 1.78 (0.92-3.44) | 0.09 |
| NOTUM | 1.81 | 0.70105693 | 2.02 (1.22-3.33) | 0.01 |
| CPS1 | 1.51 | 0.74508978 | 2.11 (1.03-4.30) | 0.04 |
FC, fold change; HR, hazard ratio; CI, confidence interval.
a
The difference in the expression of seven genes between the group with and without distant metastasis was calculated using the limma package in R software.
b
The coefficients, hazard ratios, 95% confidence intervals, and P values of seven genes were calculated using a multivariate Cox proportional hazards regression model.