Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Sep 16;12:734110. doi: 10.3389/fimmu.2021.734110

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 van Dorsten, Wagh, Moore and Morris

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Neutralization titers of single, dual, and triple combinations of scFv. Heat map showing IC₅₀ neutralization titers in μg/mL for single (A), dual (B), and triple (C) combinations of scFv against a panel of 17 subtype A, B, and C viruses. Viruses insensitive to individual bNAbs are shown as >30μg/mL. The fold improvement in IC₅₀ titers of the dual and triple combinations relative to the IC₅₀ of the best scFv in the combination is included in (B, C). Values with >3-fold increase or decrease in neutralization are shown in bold. Geometric mean potency is included at the bottom of each table. Each scFv is present in the combination at the titer indicated.