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. 2021 Sep 16;12:670425. doi: 10.3389/fendo.2021.670425

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Copyright © 2021 Kurdiova, Balaz, Kovanicova, Zemkova, Kuzma, Belan, Payer, Gasperikova, Dieplinger, Ukropcova and Ukropec

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Serum afamin concentrations and hepatic lipid content, measured by ¹H-MR spectroscopy (study 1). (A) Serum afamin correlates positively with hepatic lipids (Pearson linear correlation) (B) Stratification of the study population into quintiles according to hepatic lipid content. Data are presented as mean ± SEM. *p < 0.05; **p < 0.01; ***p < 0.001; 1-way ANOVA followed by Tukey post-hoc test; lean-healthy; ■ obese-healthy; Δ obese -prediabetes, obese - type 2 diabetes.

Inline graphic — Serum afamin concentrations and hepatic lipid content, measured by ¹H-MR spectroscopy (study 1). (A) Serum afamin correlates positively with hepatic lipids (Pearson linear correlation) (B) Stratification of the study population into quintiles according to hepatic lipid content. Data are presented as mean ± SEM. *p < 0.05; **p < 0.01; ***p < 0.001; 1-way ANOVA followed by Tukey post-hoc test; lean-healthy; ■ obese-healthy; Δ obese -prediabetes, obese - type 2 diabetes.