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. 2021 Sep 16;12:670425. doi: 10.3389/fendo.2021.670425

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Copyright © 2021 Kurdiova, Balaz, Kovanicova, Zemkova, Kuzma, Belan, Payer, Gasperikova, Dieplinger, Ukropcova and Ukropec

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Associations of (A) serum afamin concentrations with hepatic lipids, glycemia AUC and average daily steps count determined during the entire 12-week exercise intervention in study 2. Associations of (B) changes in serum afamin concentrations and changes in clinical parameters, induced by the 3-month exercise training intervention. Δ: value after training intervention (trained) – value before training (untrained); AUC, area under the curve; HOMA-IR, index of insulin resistance; oGTT, oral glucose tolerance test; VAT, visceral adipose tissue (assessed by MRI); Pearson linear correlation.