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. 2021 Sep 16;12:739000. doi: 10.3389/fmicb.2021.739000

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Copyright © 2021 Birikmen, Bohnsack, Tran, Somayaji, Bohnsack and Ebersberger.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Domain architecture comparison of Xpo5 between human and fungal orthologs. The two Pfam domains linked to import/export activity of human Xpo5, IBN_N (Pfam ID: PF03810) and Xpo1 (Pfam ID: PF08389) are still present in an early branching fungus and were secondarily lost in yeast. The phylogenetic relationships of the three taxa are indicated by the tree. Hsa, Homo sapiens; Pve, Podila verticillata (Mucoromycota); and Sce, Saccharomyces cerevisiae.