Table 7. Direct comparison of the mean CMT between naïve and non-naïve patients.

CMT (µm)	Naïve patients	Non-naïve patients	P	Effect size, η2
Baseline	507.6±117.8	488.3±175.3	0.250	0.025
2wk	411.6±101.3	681.0±325.3	--a
Month 1	419.1±130.4	482.0±345.9	--a
Month 2	348.9±70.3	346.0±142.2	0.258	0.037
Month 3	390.8±132.7	408.2±269.2	0.482	0.029
Month 4	429.9±128.2	381.4±143.0	0.975b	0.001
Month 6	408.1±109.2	378.3±111.3	0.643	0.007

CMT: Central macular thickness; SD: Standard deviation. ^aNo comparison was performed for these 2 groups due to low number of patients. ^bAfter adjusting for significantly different baseline characteristics (duration of DME), it is suggested that the duration of edema does not influence the differences between naïve and non-naïve in respect to CMT.

mean±SD