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. 2021 Sep 30;224(Suppl 4):S379–S386. doi: 10.1093/infdis/jiaa588

Table 1.

Clinical and Epidemiological Features of Smallpox and Considerations for Certification

Feature Indications of Smallpox
Incubation period 14–17 d
Syndrome visible Yes (eruption)
Recognized by public Yes (eruption)
Asymptomatic carriers None
Transmission mode Respiratory
Vector/reservoir Human
Secondary attack rate among susceptible persons High (40%–90%)