EXHIBIT 3:
Predicted means and probabilities of chronic conditions among enrollees in US commercial insurance plans, by transgender status, weighted, 2001–19
| Transgender | Cisgender | |
|---|---|---|
| Total morbidity score (mean) | 3.00 | 1.99 |
| Cardiovascular conditions (%) | ||
| Hypertension | 27.27 | 32.64 |
| Cardiac arrhythmia | 17.25 | 12.56 |
| Valvular disease | 8.96 | 7.50 |
| Peripheral vascular disorders | 7.31 | 8.06 |
| Congestive heart failurea | 4.95 | 3.68 |
| Coagulopathy | 4.44 | 3.03 |
| Pulmonary circulation disorders | 2.88 | 2.24 |
| Neurological conditions (%) | ||
| Other neurological disorders | 8.09 | 5.34 |
| Paralysis | 1.30 | 0.97 |
| Weight, diabetic, and thyroid conditions (%) | ||
| Obesity | 21.87 | 15.62 |
| Fluid and electrolyte disorders | 15.54 | 10.16 |
| Hypothyroidism | 19.13 | 12.90 |
| Diabetes | 12.88 | 13.90 |
| Abnormal weight loss | 7.80 | 4.35 |
| Mental health and substance use (%) | ||
| Depression | 56.46 | 19.86 |
| Drug use disorder | 8.12 | 3.21 |
| Psychoses | 5.81 | 1.44 |
| Alcohol use disordera | 5.25 | 3.20 |
| Other chronic conditions (%) | ||
| Chronic pulmonary disease | 26.29 | 18.13 |
| Blood loss or deficiency anemia | 10.75 | 6.54 |
| Liver diseasea | 9.22 | 5.97 |
| Renal failurea | 5.61 | 4.06 |
| Rheumatoid arthritis/collagen | 7.88 | 5.30 |
| Cancerb | 5.12 | 5.05 |
| AIDS/HIV | 1.51 | 0.29 |
| Peptic ulcer disease excluding bleeding | 2.13 | 1.25 |
source Authors’ analysis derived from administrative data from Optum’s Clinformatics Data Mart Database, 2001–19. notes The data source included deidentified insurance claims for privately insured and Medicare Advantage enrollees. Total morbidity score was determined using the Elixhauser Comorbidity Index. The underlying transgender numbers vary as a result of our transgender identification criteria, as some chronic condition and transgender exclusion codes overlap with those of the Elixhauser Comorbidity Index. So as to not bias our estimates downward, we removed people from our calculations who were identified as transgender only because they fell into an inclusion category that required that they did not have the condition being analyzed. See Jasuja GK, et al., note 3 in text, for more detail. Sample sizes are in exhibit 1 except where noted. p < 0.001 for all variables.
Transgender n = 35,631.
Transgender n = 31,124.