Table 2.

Immunohistochemical and molecular profile of lung adenocarcinoma and breast cancer.

IHC or Molecular Characteristic	Breast Cancer (Prevalence)	Lung Adenocarcinoma (Prevalence)
GCDFP-15	60%	5.2–15%
GATA-3	67–95%	8%
Napsin A	14.6%	84%
TTF-1	2.4–2.8%	70–80%
ER	80%	7.6–27.2%
PR	60%	1.6–54.8%
EGFR-activating mutations	3–11% (TNBC)	30.3%

EGFR: epidermal growth factor receptor; ER: estrogen receptors; GATA-3: GATA-binding protein 3; GCDFP-15: gross cystic disease fluid protein 15; IHC: immunohistochemical; PR: progesterone receptor; TNBC: triple-negative breast cancer; TTF-1: thyroid transcription factor-1.