Table 3.
Prognostic factors of radiographic progression-free survival using a Cox proportional hazards regression.
| Characteristic | Statistic | N | Hazard Ratio (95% CI) | p-Value |
|---|---|---|---|---|
| Age at CyberKnife Treatment | /Year | 62 | 1.01 (0.97, 1.07) | 0.59 |
| Lesion Type | Primary vs. Recurrence | 62 | 0.98 (0.30, 3.27) | 0.98 |
| Location | Parafalcine/Parasagittal Base of Skull Convexity Other |
62 | Reference 0.74 (0.12, 4.44) 1.26 (0.25, 6.31) 1.88 (0.17, 20.94) |
0.83 |
| Multiple Lesions | N vs. Y | 62 | 2.16 (0.28, 16.71) | 0.46 |
| Perilesional Edema | N vs. Y | 62 | 0.58 (0.13, 2.66) | 0.48 |
| First diagnosis to CyberKnife | /Month | 48 | 0.93 (0.61, 1.43) | 0.75 |
| Prior Resection | Y vs. N | 62 | 1.19 (0.36, 3.96) | 0.78 |
| Prior Recurrence | Y vs. N | 62 | 1.01 (0.30, 3.36) | 0.99 |
| Size (cc) | /Log-Unit | 62 | 1.43 (0.84, 2.44) | 0.19 |
| PTV (mm3) | /Log-Unit | 62 | 2.17 (0.97, 4.84) | 0.058 |
| Prescription Isodose | /Unit | 62 | 0.95 (0.86, 1.06) | 0.38 |
| Maximum Dose | /100 Units | 62 | 1.12 (1.00, 1.26) | 0.052 |
| Conformity Index | >Median vs. < = Median | 62 | 0.19 (0.04, 0.86) | 0.032 |
| New Conformity Index | >Median vs. < = Median | 62 | 0.34 (0.09, 1.26) | 0.11 |
| Homogeneity Index | /0.01 Units | 62 | 1.05 (0.99, 1.13) | 0.13 |
| Dose | /100 Units | 62 | 1.15 (0.96, 1.38) | 0.12 |
| Fractions | 3 vs. 5 | 62 | 0.34 (0.10, 1.15) | 0.083 |
| Multi-variable Results | ||||
| Conformity Index | /0.01 units | 62 | 0.92 (0.84, 1.00) | 0.047 |