Table 5.
Probiotics speculated to exhibit anti-Alzheimer activity.
| Probiotics | Condition | Concentration | Evidence | Ref |
|---|---|---|---|---|
| B. breve A1 | Patients with mild cognitive impairment | 2.0 × 1010 CFU | Can maintain cognitive function presented to significantly lift MMSE and improve POMS2 and GSRS scores | [127] |
| L. acidophilus, L. casei, B. bifidum, and L. fermentum | AD Patients | 2 × 109 CFU | Improved MMSE and significantly decreased MDA, hs-CRP levels, and HOMA-B index | [128] |
| L. casei W56, L. lactis W19, L. acidophilus, W22, B. lactis W52, L. paracasei W20, L. plantarum W62, B. lactis W51, B. bifidum W23, and L. salivarius W24 | Not specified | Influenced gut bacteria composition and serum tryptophan metabolism | [112] | |
| B. bifidum, B. longum, and selenium | 2 × 109 CFU + 200 μg | Improved the features of metabolic profile and refined cognitive functions and significantly increased TAC and GSH, regulated TNF-α, PPAR-γ, and LDLR | [129] | |
| Acetobacter aceti, L. delbrueckii, L. fermentum, L. fructivorans, E. faecium, L. kefiranofaciens | 7.5 × 107 CFU | Induced beneficially preventive effects on cognitive dysfunction, systemic inflammation, oxidative stress, and cell damage, etc. | [130] | |
| B. longum, L. acidophilus, and E. faecalis | Elderly patients for elective orthopedic/colorectal surgery | <1.0 × 107 CFU | Prevented the postoperative cognitive impairments | [131] |