Figure 3. Genetic Correlations for Clinical and Symptom-Based Depression With Cardiometabolic and Mental Health Traits.

Correlations are shown for samples with East Asian ancestry (A) and European ancestry (B) for the depression studies. For the cardiometabolic and mental health traits, publicly available summary statistics from studies with European ancestry samples were used. Blue bars represent the clinical outcome definition, and orange bars the symptom-based outcome. BMI indicates body mass index; CAD, coronary artery disease; T2D, type 2 diabetes.

^aGenetic correlations statistically different from zero.