Table 1. Baseline characteristics of adults with esophageal cancer in relation to nutritional procedure received up to 10 days after the index date (start of neoadjuvant therapy). Kaiser Permanente Northern California, 2010–2017.
Baseline characteristic | Nutritional counseling with no procedure, N=307 | J-tube, N=39 | Stent, N=20 | P value | ||||||
---|---|---|---|---|---|---|---|---|---|---|
N | % | N | % | N | % | |||||
Year of cancer diagnosis | ||||||||||
2010–2012 | 91 | 30 | 19 | 49 | 2 | 10 | <0.001 | |||
2013–2015 | 126 | 41 | 17 | 44 | 6 | 30 | ||||
2016–2017 | 90 | 29 | 3 | 8 | 12 | 60 | ||||
Histologic type | ||||||||||
Adenocarcinoma | 189 | 62 | 26 | 67 | 13 | 65 | 0.77** | |||
Squamous cell | 96 | 31 | 12 | 31 | 7 | 35 | ||||
Other | 22 | 7 | 1 | 3 | 0 | 0 | ||||
Stage at diagnosis | ||||||||||
II | 96 | 31 | 15 | 38 | 9 | 45 | 0.33 | |||
III | 211 | 69 | 24 | 62 | 11 | 55 | ||||
Age at diagnosis, years | ||||||||||
18–59 | 58 | 19 | 7 | 18 | 5 | 25 | 0.21** | |||
60–69 | 108 | 35 | 20 | 51 | 7 | 35 | ||||
70–79 | 108 | 35 | 12 | 31 | 7 | 35 | ||||
80–89 | 33 | 11 | 0 | 0 | 1 | 5 | ||||
Gender | ||||||||||
Male | 241 | 79 | 31 | 79 | 13 | 65 | 0.36 | |||
Female | 66 | 22 | 8 | 21 | 7 | 35 | ||||
Race/ethnicity | ||||||||||
Asian | 33 | 11 | 2 | 5 | 0 | 0 | 0.61** | |||
Black | 13 | 4 | 1 | 3 | 1 | 5 | ||||
Hispanic, any race | 28 | 9 | 2 | 5 | 2 | 10 | ||||
White | 210 | 68 | 32 | 82 | 17 | 85 | ||||
Other | 23 | 7 | 2 | 5 | 0 | 0 | ||||
Body mass index*, kg/m2 | ||||||||||
Underweight (<18.5) | 7 | 2 | 0 | 0 | 2 | 10 | 0.20 | |||
Healthy weight (18.5–24.9) | 100 | 33 | 10 | 26 | 5 | 25 | ||||
Overweight (25–29.9) | 97 | 32 | 15 | 38 | 4 | 20 | ||||
Obese (30+) | 103 | 34 | 14 | 36 | 9 | 45 | ||||
Smoking | ||||||||||
Ever | 210 | 68 | 22 | 56 | 18 | 90 | 0.02** | |||
Never | 91 | 30 | 13 | 33 | 2 | 10 | ||||
Unknown | 6 | 2 | 4 | 10 | 0 | 0 | ||||
Charlson comorbidity | ||||||||||
0 | 106 | 35 | 14 | 26 | 4 | 20 | 0.71** | |||
1–2 | 173 | 56 | 21 | 60 | 14 | 70 | ||||
≥3 | 28 | 9 | 4 | 14 | 2 | 10 | ||||
Median %TWL from diagnosis to index | 0.7% | 2.6% | 4.1% | <0.01 |
*, most recent measurement in the 2 years preceding diagnosis; **, P values were computed from chi-square test, Fisher’s exact test for small cell counts, and Kruskal-Wallis test for medians.