Table 2. Relationships of clinical laboratory features with the COA-NLR in individuals with NSCLC.
| Variables | COA-NLR 0 (n=149) | COA-NLR 1 (n=108) | COA-NLR 2 (n=36) | P value |
|---|---|---|---|---|
| Age, years | 57±9 | 60±9 | 61±10 | 0.063 |
| BMI, kg/m2 | 23±2.9 | 23±3.3 | 22±3.1 | 0.077 |
| OS (months) | 59±22 | 49±26 | 36±27 | <0.001 |
| CRP, mg/dL | 1.1±1.2 | 1.7±1.9 | 2.6±1.6 | 0.001 |
| WBC, 109/L | 6.9±1.7 | 8.5±2.2 | 10.0±2.6 | <0.001 |
| Neutrophil, 109/L | 3.8±1.2 | 5.7±2.2 | 7.0±2.0 | <0.001 |
| Lymph, 109/L | 2.3±0.6 | 1.8±0.5 | 1.9±0.6 | <0.001 |
| NLR | 1.7±0.5 | 3.5±2.9 | 4.0±1.6 | <0.001 |
| Hb, g/L | 137±14 | 135±15 | 125±14 | <0.001 |
| PLT, 109/L | 242±70 | 257±76 | 342±121 | <0.001 |
| Alb, g/L | 40±2.6 | 37±3.9 | 32±2.4 | <0.001 |
| Glucose, mmol/L | 5.5±1.0 | 5.6±1.5 | 5.2±1.3 | 0.023 |
| LDH, U/L | 147±24 | 181±110 | 139±25 | 0.044 |
| ALT, U/L | 20.9±15.9 | 20.9±13.6 | 29.6±30.4 | 0.311 |
COA-NLR, combination of albumin concentration and neutrophil-to-lymphocyte ratio; NSCLC, non-small cell lung cancer; BMI, body mass index; OS, overall survival; CRP, C-reactive protein; WBC, white blood cell; NLR, neutrophil-to-lymphocyte ratio; Hb, hemoglobin; PLT, platelet; Alb, albumin; LDH, lactate dehydrogenase; ALT, alanine transaminase.