Table 3.

Immunohistochemical detection of Ki-67, p53, E-cadherin and 8-OHdG

	Nodular gastritis	Non-nodular gastritis	p value
Number of case	35	36
Greater curvature of the antrum
Ki-67 labeling index	24.05 ± 14.98	21.53 ± 15.61	0.245
p53 (DO-7) labeling index	4.14 ± 2.78	3.33 ± 2.32	0.094
E-cadherin	1.00 ± 0.62	1.47 ± 0.85	0.0047
8-OHdG	1.77 ± 0.69	1.86 ± 0.68	0.291
Greater curvature of the corpus
Ki-67 labeling index	14.55 ± 12.14	12.98 ± 13.09	0.3
p53 (DO-7) labeling index	3.06 ± 1.94	2.03 ± 1.99	0.015
E-cadherin	1.16 ± 0.81	1.48 ± 0.71	0.0427
8-OHdG	1.60 ± 0.65	1.64 ± 0.59	0.397

E-cadherin, 8-OHdG: scored as: 0 for no staining, 1 for scattered cells to 33% staining, 2 for 33% to 66% staining, and 3 for diffuse staining in nearly all cells. Average ± SD. Statistical analysis was used Student’s t test.