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A-443654 reduces α-synuclein in iPSC-derived dopaminergic neurons.A, western blot of normal and 3XSNCA iPSC-derived dopaminergic neurons showing the presence of α-synuclein monomers and the response to A-443654. B, quantification of the relative levels of α-synuclein monomers. ∗∗p < 0.01, Student’s t test with Bonferroni correction. iPSC, induced pluripotent stem cell.
