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. 2021 Sep 30;22(Suppl 13):376. doi: 10.1186/s12859-021-04297-z

Table 12.

The intersection of the first 10 pathways (sorted by the relevance of p value 0.005) obtained from pathDIP performing PEA using CC genes lists and the Reactome database

Pathway Name p value FDRc Bc
(1) Metabolism of proteins 3.18 × 10-74 6.31 × 10-71 6.31 × 10-71
(2) Immune System 1.46 × 10-60 9.64 × 10-58 2.89 × 10-57
(3) Post-translational protein modification 6.40 × 10-49 3.17 × 10-46 1.27 × 10-45
(4) Disease 4.02 × 10-37 1.33 × 10-34 7.96 × 10-34
(5) Gene expression (Transcription) 1.34 × 10-36 3.79 × 10-34 2.66 × 10-33
(6) RNA Polymerase II Transcription 1.01 × 10-29 2.00 × 10-27 2.00 × 10-26
(7) Innate Immune System 4.51 × 10-27 8.13 × 10-25 8.95 × 10-24
(8) Cell Cycle 2.07 × 10-25 2.93 × 10-23 4.11 × 10-22
(9) Generic Transcription Pathway 2.94 × 10-25 3.88 × 10-23 5.83 × 10-22
(10) Transcriptional Regulation by TP53 3.27 × 10-21 3.09 × 10-19 6.48 × 10-18

In the table, FDRc represents the corrected p value using FDR corrector, and Bc refers to the corrected p value using Bonferroni corrector