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. 2021 Sep 30;22(Suppl 13):376. doi: 10.1186/s12859-021-04297-z

Table 15.

The first 10 enriched pathways (sorted by the relevance of p value 0.005) obtained from BiP performing PEA using TC genes lists and the Reactome database

Pathway Name p value FDRc Bc
(1) Mitotic Prometaphase 7.74 × 10-14 2.52 × 10-11 1.51 × 10-10
(2) Membrane Trafficking 3.61 × 10-12 8.80 × 10-10 7.04 × 10-09
(3) Signaling by Rho GTPases 7.67 × 10-12 1.15 × 10-09 1.50 × 10-08
(4) Post-translational protein modification 1.49 × 10-11 1.94 × 10-09 2.91 × 10-08
(5) Extracellular matrix organization 1.40 × 10-10 1.36 × 10-08 2.72 × 10-07
(6) Metabolism of proteins 2.48 × 10-10 2.11 × 10-08 4.85 × 10-07
(7) M Phase 3.18 × 10-10 2.48 × 10-08 6.20 × 10-07
(8) Cell Cycle, Mitotic 1.17 × 10-09 7.86 × 10-08 2.28 × 10-06
(9) Mitotic G1-G1/S phases 1.17 × 10-09 7.59 × 10-08 2.28 × 10-06
(10) Cell Cycle 1.58 × 10-09 9.64 × 10-08 3.08 × 10-06

In the table, FDRc represents the corrected p value using FDR corrector, and Bc refers to the corrected p value using Bonferroni corrector