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. 2021 Sep 30;22(Suppl 13):376. doi: 10.1186/s12859-021-04297-z

Table 16.

The first 10 enriched pathways (sorted by the relevance of p value 0.005) obtained from pathDIP performing PEA using TC genes lists and the Reactome database

Pathway Name p value FDRc Bc
(1) Immune System 1.56 × 10-28 2.90 × 10-25 2.90 × 10-25
(2) Metabolism 9.59 × 10-28 5.94 × 10-25 1.78 × 10-24
(3) Metabolism of proteins 6.89 × 10-27 3.20 × 10-24 1.28 × 10-23
(4) Cell Cycle, Mitotic 5.72 × 10-26 1.52 × 10-23 1.06 × 10-22
(5) Post-translational protein modification 3.01 × 10-24 6.20 × 10-22 5.58 × 10-21
(6) Membrane Trafficking 1.37 × 10-21 2.54 × 10-19 2.54 × 10-18
(7) Neutrophil degranulation 3.17 × 10-18 4.91 × 10-16 5.90 × 10-15
(8) M Phase 5.68 × 10-16 4.59 × 10-14 1.06 × 10-12
(9) Disease 7.65 × 10-14 5.07 × 10-12 1.42 × 10-10
(10) Signaling by Receptor Tyrosine Kinases 4.96 × 10-13 2.88 × 10-11 9.21 × 10-10

In the table, FDRc represents the corrected p value using FDR corrector, and Bc refers to the corrected p value using Bonferroni corrector