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. 2021 Sep 30;22(Suppl 13):376. doi: 10.1186/s12859-021-04297-z

Table 6.

The intersection of the first 10 pathways obtained from CePa by performing TEA using EC genes lists and the KEGG database. The table summarises the values obtained for each topology measure employed by CePa

Name weight in degree out degree betweenness in reachability out reachability
(1) Pyrimidine biosynthesis 0.031 0.029 0.146 0.037 0.0056 0.034
(2) Inactivation of APC C via direct inhibition of the APC C complex 0.044 0.0290 0.034 0.037 0.0056 0.034
(3) Removal of licensing factors from origins 0.031 0.029 0.034 0.037 0.047 0.034
(4) CDT1 association with the CDC6 ORC origin complex 0.031 0.029 0.066 0.062 0.047 0.034
(5) NCAM signaling for neurite out growth 0.031 0.029 0.034 0.085 0.121 0.034
(6) Switching of origins to a post replicative state 0.031 0.029 0.034 0.037 0.047 0.034
(7) Fanconi Anemia pathway 0.031 0.029 0.034 0.0377 0.047 0.041
(8) Telomere C strand Lagging Strand Synthesis 0.0056 0.062 0.066 0.0053 0.0056 0.041
(9) Branched chain amino acid catabolism 0.031 0.029 0.089 0.0053 0.047 0.034
(10) Removal of DNA patch containing a basic residue 0.031 0.062 0.034 0.085 0.087 0.034