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. 2021 Sep 30;22(Suppl 13):376. doi: 10.1186/s12859-021-04297-z

Table 7.

The intersection of the first 10 pathways (sorted by the relevance of p value 0.005) obtained from pathDIP performing PEA using EC genes lists and the KEGG database

Pathway Name p value FDRc Bc
(1) Alzheimer disease 2.47 × 10-10 3.46 × 10-08 6.93 × 10-08
(2) Parkinson disease 7.46 × 10-09 5.24 × 10-07 2.10 × 10-06
(3) Non-alcoholic fatty liver disease (NAFLD) 9.14 × 10-08 5.13 × 10-06 2.57 × 10-05
(4) Cellular senescence 1.31 × 10-06 4.60 × 10-05 3.68 × 10-04
(5) Huntington disease 4.98 × 10-06 1.40 × 10-04 1.40 × 10-03
(6) Human T-cell leukemia virus 1 infection 8.80 × 10-06 2.25 × 10-04 2.47 × 10-03
(7) Oxidative phosphorylation 9.73 × 10-06 2.28 × 10-04 2.73 × 10-03
(8) Apoptosis 1.28 × 10-05 2.76 × 10-04 3.59 × 10-03
(9) Mineral absorption 1.69 × 10-05 3.17 × 10-04 4.75 × 10-03
(10) Cardiac muscle contraction 1.84 × 10-05 3.24 × 10-04 5.18 × 10-03

In the table, FDRc represents the corrected p value using FDR corrector, and Bc refers to the corrected p value using Bonferroni corrector