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. 2021 Sep 30;22(Suppl 13):376. doi: 10.1186/s12859-021-04297-z

Table 8.

The intersection of the first 10 pathways (sorted by the relevance of p value 0.005) obtained from BiP, performing PEA using TC genes lists and the KEGG database

Pathway Name p value FDRc Bc
(1) Metabolic pathways 1.59 × 10-111 4.98 × 10-109 4.98 × 10-109
(2) Cytokine-cytokine receptor interaction 1.02 × 10-40 1.60 × 10-38 3.21 × 10-38
(3) Pathways in cancer 2.50 × 10-30 2.62 × 10-28 7.85 × 10-28
(4) Pathways of neurodegeneration-multiple diseases 7.56 × 10-26 5.93 × 10-24 2.37 × 10-23
(5) Ubiquitin mediated proteolysis 1.75 × 10-17 3.44 × 10-16 5.50 × 10-15
(6) Neuroactive ligand-receptor interaction 2.72 × 10-17 4.75 × 10-16 8.56 × 10-15
(7) Oxidative phosphorylation 7.94 × 10-17 1.25 × 10-15 2.49 × 10-14
(8) Ribosome 2.02 × 10-16 2.89 × 10-15 6.35 × 10-14
(9) Protein processing in endoplasmic reticulum 1.39 × 10-15 1.62 × 10-14 4.37 × 10-13
(10) Human immunodeficiency virus 1 infection 2.06 × 10-15 2.16 × 10-14 6.47 × 10-13

In the table, FDRc represents the corrected p value using FDR corrector, and Bc refers to the corrected p value using Bonferroni corrector