Table 9.

The 10 enriched pathways with CePa using the two TC genes lists and the KEGG database. The table summarises the values obtained for each topology measure employed by CePa

Name	Weight	In degree	Out degree	Betweenness	In reachability	Out reachability
(1) Pyrimidine biosynthesis	0.034	0.034	0.180	0.041	0.034	0.029
(2) Inactivation of APC C via direct inhibition of the APC C complex	0.047	0.0050	0.029	0.041	0.034	0.047
(3) Generation of second messenger molecules	0.034	0.097	0.0059	0.118	0.091	0.118
(4) Removal of licensing factors from origins	0.034	0.034	0.029	0.041	0.034	0.029
(5) CDT1 association with the CDC6 ORC origin complex	0.047	0.034	0.041	0.0058	0.071	0.029
(6) Association of licensing factors with the pre replicative complex	0.205	0.034	0.188	1	0.066	0.233
(7) NCAM signaling for neurite out growth	0.034	0.062	0.029	0.068	0.091	0.029
(8) Switching of origins to a post replicative state	0.034	0.034	0.029	0.041	0.034	0.029
(9) Fanconi Anemia pathway	0.034	0.034	0.029	0.041	0.034	0.029
(10) Telomere C strand Lagging Strand Synthesis	0.0051	0.065	0.041	0.082	0.075	0.029