Table 1.
Clinical data of patients in two groups
| Item | Sequencing of genome-wide SNP and DNA methylation | Verification of genome-wide SNP and DNA methylation | ||||
|---|---|---|---|---|---|---|
| non-HLF (n = 5) |
HLF (n = 5) |
P value | non-HLF (n = 10) |
HLF (n = 10) |
P value | |
| Age/years | 58 ± 5 | 75 ± 5 | 5.80E-02 | 52 ± 5 | 69 ± 3 | 2.00E-02 |
| LF thickness/cm | 0.28 ± 0.01 | 0.52 ± 0.03 | 6.12E-05 | 0.31 ± 0.01 | 0.52 ± 0.02 | 6.29E-09 |
| Gender | 3F/2M | 4F/1M | 5F/5M | 8F/2M | ||
| Lumbar level | L4/5 | L4/5 | L4/5 | L4/5 | ||
Data are presented as the mean ± S.E.M.. P < 0.05 is considered to be significant. LF, ligamentum flavum. Non-HLF, LDD patients without ligamentum flavum hypertrophy (LF thickness ≤ 4 mm). HLF, LDD patients with ligamentum flavum hypertrophy (LF Thickness > 4 mm). F/M, female/male