Table 3.
Multivariate Analysis of 3 Models of Prognostic Factors in Patients With Cecum Cancer.
| Prognostic factors | Cox model | Fine-gray model | CS model | ||||||
|---|---|---|---|---|---|---|---|---|---|
| P-value | HR | 95%CI | P-Value | HR | 95%CI | P-Value | HR | 95%CI | |
| Age | |||||||||
| ≤65 | reference | reference | reference | ||||||
| >65 | <0.001 | 1.98 | 1.92-2.04 | 0.0011 | 1.07 | 1.03-1.11 | <0.001 | 1.30 | 1.25-1.35 |
| Race | |||||||||
| white | reference | reference | reference | ||||||
| black | <0.001 | 1.09 | 1.05-1.13 | <0.001 | 1.16 | 1.10-1.23 | <0.001 | 1.17 | 1.12-1.24 |
| other | <0.001 | 0.83 | 0.78-0.88 | 0.1362 | 1.06 | 0.98-1.15 | 0.9613 | 1.00 | 0.93-1.08 |
| AJCC Stage | |||||||||
| Ⅰ | reference | reference | reference | ||||||
| Ⅱ | <0.001 | 1.30 | 1.25-1.36 | <0.001 | 2.08 | 1.89-2.30 | <0.001 | 2.15 | 1.95-2.37 |
| Ⅲ | <0.001 | 1.57 | 1.44-1.70 | <0.001 | 3.76 | 3.31-4.28 | <0.001 | 4.03 | 3.56-4.56 |
| Ⅳ | <0.001 | 6.10 | 5.65-6.60 | <0.001 | 13.33 | 11.78-15.08 | <0.001 | 19.66 | 17.45-22.16 |
| Surgery | |||||||||
| No | reference | reference | reference | ||||||
| Yes | <0.001 | 0.32 | 0.30-0.35 | <0.001 | 0.50 | 0.44-0.57 | <0.001 | 0.34 | 0.30-0.37 |
| Radiotherapy | |||||||||
| No | reference | reference | reference | ||||||
| Yes | <0.001 | 0.53 | 0.51-0.55 | <0.001 | 0.74 | 0.70-0.77 | <0.001 | 0.57 | 0.55-0.60 |
| Differentiation Grade | |||||||||
| Ⅰ | reference | reference | reference | ||||||
| Ⅱ | 0.0582 | 1.06 | 1.00-1.11 | 0.003 | 1.14 | 1.05-1.24 | <0.001 | 1.17 | 1.07-1.27 |
| Ⅲ | <0.001 | 1.37 | 1.30-1.45 | <0.001 | 1.45 | 1.33-1.59 | <0.001 | 1.62 | 1.49-1.77 |
| Ⅳ | <0.001 | 1.53 | 1.41-1.65 | <0.001 | 1.46 | 1.30-1.65 | <0.001 | 1.77 | 1.58-1.99 |
| Regional lymph nodes metastasis | |||||||||
| No | reference | reference | reference | ||||||
| Yes | <0.001 | 0.92 | 0.89-0.96 | 0.0258 | 1.08 | 1.03-1.15 | 0.0335 | 1.06 | 1.01-1.12 |
| Chemotherapy | |||||||||
| no | reference | reference | reference | ||||||
| yes | <0.001 | 0.56 | 0.54-0.58 | <0.001 | 0.88 | 0.84-0.92 | <0.001 | 0.66 | 0.63-0.70 |
| Tumor Size | |||||||||
| I | reference | reference | reference | ||||||
| Ⅱ | 0.0034 | 1.15 | 1.05-1.26 | 0.0018 | 1.35 | 1.12-1.63 | 0.0032 | 1.33 | 1.10-1.60 |
| Ⅲ | <0.001 | 1.27 | 1.16-1.39 | <0.001 | 1.60 | 1.33-1.93 | <0.001 | 1.60 | 1.33-1.93 |
| IV | <0.001 | 1.36 | 1.24-1.49 | <0.001 | 1.80 | 1.49-2.16 | <0.001 | 1.83 | 1.53-2.21 |
| Sex | |||||||||
| male | reference | reference | reference | ||||||
| female | 0.6613 | 0.99 | 0.97-1.02 | 0.1361 | 0.97 | 0.94-1.01 | 0.0707 | 0.97 | 0.93-1.00 |
Abbreviations: HR, Hazard radio; CI, Confidence interval; CS, Cause-specific hazard.
Note: Tumor size Ⅰ: Largest dimension, or the diameter less than or equal to 1cm; Tumor size Ⅱ: Largest dimension, or the diameter greater than 1cm and less than or equal to 3cm; Tumor size Ⅲ: Largest dimension, or the diameter greater than 3cm and less than or equal to 5cm; Tumor size Ⅳ: Largest dimension, or the diameter more than 5 cm.