Table 3. EC50 and Emax Values for ATP/BzATP-Induced Response in the Absence and Presence of Different Concentrations of Inhibitor.
| ATP/BzATP dose–response curve | EC50 (μM) | Emax (%) | |
|---|---|---|---|
| h-P2X2R | ATP without inhibitor | 1.083 | 100 |
| 0.2 μM of 6h | 1.014 | 82 | |
| 0.6 μM of 6h | 1.848 | 74 | |
| 0.8 μM of 6h | 1.413 | 51 | |
| h-P2X4R | ATP without inhibitor | 2.588 | 100 |
| 1 μM of 7e | 1.634 | 73 | |
| 3 μM of 7e | 1.125 | 57 | |
| 6 μM of 7e | 2.192 | 43 | |
| h-P2X7R | BzATP without inhibitor | 5.497 | 100 |
| 0.5 μM of 6h | 9.489 | 77 | |
| 1.0 μM of 6h | 5.724 | 55 | |
| 2.0 μM of 6h | 6.483 | 50 | |