Table 5. Effect of Treatment with Compounds 8b, 8c, FLC, and VOR (15 mg/kg) on Systemic Candidiasis in Neutropenic Mice (n = 5) via Oral Gavage and Resulting Kidney Fungal Burden Values in Each Group.
| treatment | CFU/ga | CFU/g range |
|---|---|---|
| Ctrl | 779 ± 39.6 | 700–920 |
| 8b | 414 ± 67.7b | 220–580 |
| 8c | 438 ± 54.8b | 310–600 |
| FLC | 512 ± 63.5b | 450–690 |
| VOR | 318 ± 66.5b | 180–520 |
a
Mean ± standard deviation (SD) of triplicate samples of colony-forming units/gram of the left kidney tissue.
b
P < 0.01 compound-treated vs untreated mice.