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. 2021 Sep 16;14:727552. doi: 10.3389/fnmol.2021.727552

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Copyright © 2021 Mou, Dein, Chen, Jagdale and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Motor protein expression in MFN2 deficient spinal motor neurons. (A) The mRNA expression of anterograde and retrograde transport-associated motor protein genes in MFN2 RNAi #1, MFN2 RNAi #2, and Luc RNAi spinal motor neurons by qRT-PCR. (B) MFN2 and important motor proteins expression in D42 spinal motor neurons, including KIF1A, KIF5A, and DYNC1I1. (C) Quantification of MFN2, KIF1A, KIF5A, and DYNC1I1 band intensity, β-actin as the reference protein. Data are represented as mean ± SEM, n = 3. *p < 0.05 compared with Luc RNAi.