Figure 8.

Administration of human H19 (hH19) improves contractile force of human engineered heart tissues. (A) AAV6-mediated overexpression of H19 in human engineered heart tissue (EHT) compared to control (AAV6-empty). (B) Increased contractile force 28 days after EHT preparation. (C). Force development over time. Data are means ± SD. P-values were determined by two-tailed unpaired Student’s t-test or one-way with Bonferroni correction.