Table 5.
Haplotype distribution for SNPs-rs2071861 (CRYBA4), rs5752083 (CRYBB2), and rs5996863 (CRYBB2)
| Haplotype pair | Cases (n=282) | Controls (n=214) | OR [95% CI] | χ 2 | P |
|---|---|---|---|---|---|
| AAC | 13.91 (0.049) | 9.56 (0.045) | 1.11 [0.48, 2.58] | 0.06 | 0.810 |
| AAT | 63.90 (0.227) | 60.85 (0.284) | 0.74 [0.49, 1.11] | 2.16 | 0.142 |
| ACC | 67.00 (0.238) | 58.92 (0.275) | 0.82 [0.55, 1.23] | 0.91 | 0.340 |
| ACT | 22.19 (0.079) | 6.67 (0.031) | 2.66 [1.09, 6.43] | 5.01 | 0.025 |
| GAC | 8.67 (0.031) | 3.46 (0.016) | 1.93 [0.55, 6.81] | 1.09 | 0.297 |
| GAT | 55.52 (0.197) | 36.13 (0.169) | 1.21 [0.76, 1.92] | 0.64 | 0.425 |
| GCC | 30.43 (0.108) | 28.07 (0.131) | 0.80 [0.46, 1.38] | 0.63 | 0.426 |
| GCT | 20.38 (0.072) | 10.35 (0.048) | 1.53 [0.71, 3.31] | 1.20 | 0.274 |
SNP: Single nucleotide polymorphism, OR: Odds ratio, CI: Confidence interval. Note: Frequencies <0.03 in both cases and controls have been dropped. Global χ2=10.33, degrees of freedom=7, P=0.17