Table 2.
Reported individual symptoms between childhood-onset food allergy (COFA) and adult-onset food allergy (AOFA).
| Symptom | Total (n=202) | COFA (n=80) | AOFA (n=122) | P-value1 |
|---|---|---|---|---|
| Cutaneous, n (%) | 119 (95) | 79 (99) | 112 (92) | 0.05 |
| Hives | 117 (58) | 54 (68) | 63 (52) | 0.03 |
| Skin itching | 117 (58) | 55 (69) | 62 (51) | 0.01 |
| Flushing | 80 (40) | 41 (51) | 39 (32) | 0.008 |
| Swelling of face, lips or tongue | 116 (57) | 55 (69) | 61 (50) | 0.009 |
| Rash | 41 (20) | 20 (25) | 21 (17) | 0.21 |
| Mouth itching | 93 (46) | 46 (58) | 47 (39) | 0.01 |
| Swelling of throat | 125 (62) | 58 (73) | 67 (55) | 0.01 |
| Lower respiratory n (%) | 131 (65) | 61 (76) | 70 (57) | 0.007 |
| Trouble breathing | 109 (54) | 56 (70) | 53 (43) | <0.001 |
| Cough | 50 (25) | 24 (30) | 26 (21) | 0.18 |
| Wheezing | 80 (40) | 45 (56) | 35 (29) | <0.001 |
| Upper respiratory, n (%) | 64 (32) | 31 (39) | 33 (27) | 0.09 |
| Sneezing | 25 (12) | 11 (14) | 14 (12) | 0.67 |
| Runny nose | 34 (17) | 17 (21) | 17 (14) | 0.18 |
| Congestion | 46 (23) | 26 (33) | 20 (16) | 0.01 |
| Eye tearing, itchy, redness, n (%) | 58 (29) | 31 (39) | 27 (22) | 0.02 |
| Gastrointestinal, n (%) | 105 (52) | 53 (66) | 52 (43) | 0.001 |
| Nausea | 67 (33) | 35 (44) | 32 (26) | 0.01 |
| Vomiting | 60 (30) | 33 (41) | 27 (22) | 0.005 |
| Diarrhea | 48 (24) | 21 (26) | 27 (22) | 0.50 |
| Stomach pain | 70 (35) | 38 (48) | 32 (26) | 0.002 |
| Cardiovascular, n (%) | 46 (23) | 20 (25) | 26 (21) | 0.61 |
| Lightheadedness | 42 (21) | 18 (23) | 24 (20) | 0.72 |
| Loss of consciousness, fainting | 12 (6) | 6 (8) | 6 (5) | 0.55 |
| Other, n (%) ❈ | 49 (24) | 12 (15) | 37 (30) | 0.02 |
1
Fisher’s exact test,
❈
included itchy throat, pain in throat, numb mouth, migraine/headaches, sweats, mouthwatering, ears itch, acid reflux, sleepy, fatigue, sore joints. Significant values are bolded.