Skip to main content
. 2021 Sep 29;16(1):1053–1063. doi: 10.1515/biol-2021-0082

Figure 5.

Figure 5

miR-15a-5p interacted with EGFR in HBMECs. (a) The binding sites between miR-15a-5p and EGFR were predicted by starbase3.0 online database. (b) Luciferase activity was detected by dual-luciferase reporter assay. (c) The efficiency of miR-15a-5p mimic and inhibitor in increasing or decreasing miR-15a-5p expression was determined by qRT-PCR. (d and e) The effects of miR-15a-5p mimic and inhibitor on the mRNA and protein levels of EGFR were determined by qRT-PCR and western blot, respectively. (f and g) The impacts of ox-LDL treatment on the mRNA and protein expression of EGFR were severally determined by qRT-PCR and western blot. *P < 0.05.