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. 2021 Jul 14;10(14):e016543. doi: 10.1161/JAHA.120.016543

Figure 2. Effects of high‐fructose diet (HFr) on renal histological characteristics in Dahl salt‐resistant (DR) and Dahl salt‐sensitive (DS) rats.

Figure 2

A, Representative images of the glomerulus and the renal cortex stained with periodic acid–Schiff (PAS) (top panel), against desmin (second panel), against α‐smooth muscle actin (α‐SMA) (third panel), and Masson trichrome (bottom panel) in the control diet (Con)–fed DR (Con‐DR) rat, HFr‐fed DR (HFr‐DR) rat, Con‐fed DS (Con‐DS) rat, and HFr‐fed DS (HFr‐DS) rat groups. Index of glomerular sclerosis (IGS) (B), glomerular desmin‐positive area (C), media/lumen ratio (D), and relative interstitial volume (RIV) (E) were compared among the Con‐DR (n=6), HFr‐DR (n=6), Con‐DS (n=6), and HFr‐DS (n=6) groups. Data are presented as mean±SEM. *P<0.05, **P<0.01 compared with the Con‐DR group; ## P<0.01 compared with the Con‐DS group; † P<0.05, †† P<0.01 compared with the HFr‐DR group.