Table 1.
Patient Characteristics
| Patient Characteristics | All Patients | Nonsurgical Patients |
|---|---|---|
| Total number of patients | 1162 | 617 |
| Male | 791 (68.1) | 405 (65.6) |
| Female | 371 (31.9) | 212 (34.6) |
| Age, y | 70.2±13.5 | 71.9±13 |
| Height, cm | 173.2±11.5 | 172.7±11.9 |
| Body surface area, m2 | 1.99±0.28 | 1.99±0.3 |
| Bicuspid | 257 (22.1) | 42 (6.8) |
| Marfan, connective tissue disorders | 36 (3.1) | 16 (5.8) |
| Family history | ||
| Proven | 248 (21.3) | 114 (18.5) |
| Likely | 75 (6.5) | 35 (5.7) |
| Possible | 51 (4.4) | 33 (5.4) |
| Unknown | 136 (11.7) | 80 (13) |
| None | 652 (56.1) | 355 (57.5) |
| Previous cardiac surgeries | ||
| CABG | 37 (3.2) | 33 (5.3) |
| AVR | 64 (5.5) | 21 (3.4) |
| MVR | 13 (1.1) | 7 (1.1) |
| CABG+AVR | 17 (1.4) | 8 (1.3) |
| AVR+MVR | 2 (0.02) | 1 (0.2) |
| CABG+AVR+MVR | 2 (0.02) | 2 (0.3) |
| Ascending aorta–related death | 8 (0.69) | 8 (1.3) |
| Other cause of death | 119 (10.2) | 119 (19.3) |
| Hypertension | 716 (61.6) | 374 (60.6) |
| DM | 178 (15.3) | 75 (12.2) |
| Aortic root diameter, cm | 4.02±0.60 | 3.94±0.57 |
| Mid‐ascending aorta diameter, cm | 4.33±0.77 | 4.16±0.76 |
Data are provided as mean±SD or number (percentage). The nonsurgical group is a subsection of the all‐patients group. It was studied because the weeding out of surgical patients blunts the effect of censoring patients at the time of surgery, that is, before further aortic dilatation and adverse events. As patients with bicuspid aortic valve undergo surgery early, the nonsurgical group contains significantly fewer patients (P<0.001). AVR indicates aortic valve replacement; CABG, coronary artery bypass grafting; DM, diabetes mellitus; and MVR, mitral valve replacement.