Table 2.
Cumulative Incidence of Heart Failure Hospitalization and All‐Cause Mortality by Quartiles of Adiposity Measures in the Jackson Heart Study
| Total Events∗ | Q1† | Q2 | Q3 | Q4 | P Value‡ | |
|---|---|---|---|---|---|---|
| Pericardial adipose tissue | ||||||
| Heart failure hospitalization, No. (cumulative incidence) (95% CI) | 77 | 9 (2.7) (1.4–5.1) | 16 (4.9) (3.0–7.9) | 22 (6.7) (4.5–10.1) | 30 (9.2) (6.5–12.9) | 0.003 |
| Mortality, No. (cumulative incidence) (95% CI) | 153 | 24 (7.0) (4.7–10.3) | 33 (9.8) (7.1–13.5) | 36 (10.5) (7.7–14.3) | 60 (17.5) (13.9–22.1) | <0.001 |
| Visceral adipose tissue | ||||||
| Heart failure hospitalization, No. (cumulative incidence) (95% CI) | 168 | 29 (4.3) (3.0–6.1) | 22 (3.2) (2.1–4.9) | 53 (8.8) (6.6–11.6) | 64 (10.3) (8.1–13.1) | <0.001 |
| Mortality, No. (cumulative incidence) (95% CI) | 329 | 71 (10.9) (8.7–13.6) | 75 (11.5) (9.3–14.3) | 65 (9.6) (7.6–12.2) | 118 (17.7) (15.0–21.0) | <0.001 |
| Subcutaneous adipose tissue | ||||||
| Heart failure hospitalization, No. (cumulative incidence) (95% CI) | 168 | 47 (7.6) (5.7–10.2) | 28 (4.4) (3.0–6.5) | 48 (7.6) (5.7–10.1) | 45 (6.9) (5.1–9.3) | 0.07 |
| Mortality, No. (cumulative incidence) (95% CI) | 329 | 107 (16.4) (13.7–19.5) | 75 (11.3) (9.1–14.0) | 77 (11.8) (9.6–14.7) | 70 (10.4) (8.3–13.0) | 0.009 |
Q1 indicates quartile 1; Q2, quartile 2; Q3, quartile 3; and Q4, quartile 4.
There were totals of 1386, 2844, and 2843 participants in the pericardial adipose tissue, visceral adipose tissue, and subcutaneous adipose tissue groups, respectively.
Pericardial adipose tissue quartiles: Q1, ≤48.64 cm3; Q2, 48.65–65.80 cm3; Q3, 65.81–86.36 cm3; Q4, >86.36 cm3. Visceral adipose tissue quartiles: Q1, ≤556.23 cm3; Q2, 556.24–769.11 cm3; Q3, 769.12–1039.81 cm3; Q4, >1039.81 cm3. Subcutaneous adipose tissue quartiles: Q1, ≤1563.02 cm3; Q2, 1563.03–2181.32 cm3; Q3, 2181.33–2975.49 cm3; Q4, >2975.49 cm3.
P values to trend.